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Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation
BACKGROUND: Recent evidence suggests that endogenous arginase activity potentiates airway responsiveness to methacholine by attenuation of agonist-induced nitric oxide (NO) production, presumably by competition with epithelial constitutive NO synthase for the common substrate, L-arginine. Using guin...
Autores principales: | Maarsingh, Harm, Tio, Marieke A, Zaagsma, Johan, Meurs, Herman |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555585/ https://www.ncbi.nlm.nih.gov/pubmed/15748286 http://dx.doi.org/10.1186/1465-9921-6-23 |
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