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Evidence that central pathways that mediate defecation utilize ghrelin receptors but do not require endogenous ghrelin

In laboratory animals and in human, centrally penetrant ghrelin receptor agonists, given systemically or orally, cause defecation. Animal studies show that the effect is due to activation of ghrelin receptors in the spinal lumbosacral defecation centers. However, it is not known whether there is a p...

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Detalles Bibliográficos
Autores principales: Pustovit, Ruslan V, Callaghan, Brid, Ringuet, Mitchell T, Kerr, Nicole F, Hunne, Billie, Smyth, Ian M, Pietra, Claudio, Furness, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555902/
https://www.ncbi.nlm.nih.gov/pubmed/28801520
http://dx.doi.org/10.14814/phy2.13385