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Hypoxia-induced TET1 facilitates trophoblast cell migration and invasion through HIF1α signaling pathway

Low oxygen is a typical extrinsic factor for the regulation of trophoblast biological function, including cell migration, invasion and proliferation. Ten-eleven translocation methylcytosine dioxygenase 1 (TET1), an enzyme converting 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), is tran...

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Detalles Bibliográficos
Autores principales: Zhu, Jingping, Wang, Kai, Li, Ting, Chen, Jiayu, Xie, Dandan, Chang, Xinwen, Yao, Julei, Wu, Jinting, Zhou, Qian, Jia, Yuanhui, Duan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556046/
https://www.ncbi.nlm.nih.gov/pubmed/28808304
http://dx.doi.org/10.1038/s41598-017-07560-7