Cargando…

Hypoxia-induced TET1 facilitates trophoblast cell migration and invasion through HIF1α signaling pathway

Low oxygen is a typical extrinsic factor for the regulation of trophoblast biological function, including cell migration, invasion and proliferation. Ten-eleven translocation methylcytosine dioxygenase 1 (TET1), an enzyme converting 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), is tran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Jingping, Wang, Kai, Li, Ting, Chen, Jiayu, Xie, Dandan, Chang, Xinwen, Yao, Julei, Wu, Jinting, Zhou, Qian, Jia, Yuanhui, Duan, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556046/ https://www.ncbi.nlm.nih.gov/pubmed/28808304 http://dx.doi.org/10.1038/s41598-017-07560-7

Ejemplares similares

Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity
por: Wang, Jing, et al.
Publicado: (2017)

Hypoxia-induced expression of CXCR4 favors trophoblast cell migration and invasion via the activation of HIF-1α
por: Zhang, Zhan, et al.
Publicado: (2018)

HIF-2α, but not HIF-1α, mediates hypoxia-induced up-regulation of Flt-1 gene expression in placental trophoblasts
por: Sasagawa, Tadashi, et al.
Publicado: (2018)

HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes
por: Ali, Mohamed M., et al.
Publicado: (2020)

Dishevelled Associated Activator Of Morphogenesis (DAAM) Facilitates Invasion of Hepatocellular Carcinoma by Upregulating Hypoxia-Inducible Factor 1α (HIF-1α) Expression
por: Fang, Xiaoxu, et al.
Publicado: (2020)

TCDD Induces the Hypoxia-Inducible Factor (HIF)-1α Regulatory Pathway in Human Trophoblastic JAR Cells
por: Liao, Tien-Ling, et al.
Publicado: (2014)

Effects of hypoxia inducible factors-1α on autophagy and invasion of trophoblasts
por: Choi, Jong-Ho, et al.
Publicado: (2012)

Silencing BRIT1 Facilitates the Abilities of Invasiveness and Migration in Trophoblast Cells
por: Liu, Luping, et al.
Publicado: (2018)

Autophagy Induced by HIF1α Overexpression Supports Trophoblast Invasion by Supplying Cellular Energy
por: Yamanaka-Tatematsu, Mikiko, et al.
Publicado: (2013)

HIF1α stabilization in hypoxia is not oxidant-initiated
por: Kumar, Amit, et al.
Publicado: (2021)

Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
por: Bao, Lei, et al.
Publicado: (2018)

Hypoxia promotes the migration and invasion of human hepatocarcinoma cells through the HIF-1α–IL-8–Akt axis
por: Fei, Maoyun, et al.
Publicado: (2018)

ELTD1 facilitates glioma proliferation, migration and invasion by activating JAK/STAT3/HIF-1α signaling axis
por: Li, Junjun, et al.
Publicado: (2019)

A novel HIF-1α-integrin-linked kinase regulatory loop that facilitates hypoxia-induced HIF-1α expression and epithelial-mesenchymal transition in cancer cells
por: Chou, Chih-Chien, et al.
Publicado: (2015)

Hypoxia-induced HIF-1α promotes Listeria monocytogenes invasion into tilapia
por: Wang, Jing, et al.
Publicado: (2023)

HIF2α Upregulates the Migration Factor ODZ1 under Hypoxia in Glioblastoma Stem Cells
por: Carcelén, María, et al.
Publicado: (2022)

DNA methyltransferases and TETs in the regulation of differentiation and invasiveness of extra-villous trophoblasts
por: Logan, Philip C., et al.
Publicado: (2013)

TET1 and 5-Hydroxymethylation Preserve the Stem Cell State of Mouse Trophoblast
por: Senner, Claire E., et al.
Publicado: (2020)

Characterization and functional analysis of hypoxia-inducible factor HIF1α and its inhibitor HIF1αn in tilapia
por: Li, Hong Lian, et al.
Publicado: (2017)

Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells
por: Chen, Fangrong, et al.
Publicado: (2023)

Hypoxia Promotes Migration and Induces CXCR4 Expression via HIF-1α Activation in Human Osteosarcoma
por: Guo, Mingjun, et al.
Publicado: (2014)

Chronic Deficiency of Nitric Oxide Affects Hypoxia Inducible Factor-1α (HIF-1α) Stability and Migration in Human Endothelial Cells
por: Cattaneo, Maria Grazia, et al.
Publicado: (2011)

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
por: Mole, David R., et al.
Publicado: (2009)

HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
por: Mawambo, Gaëlle, et al.
Publicado: (2023)

Altered Expression of Hypoxia-Inducible Factor-1α (HIF-1α) and Its Regulatory Genes in Gastric Cancer Tissues
por: Wang, Jihan, et al.
Publicado: (2014)

Effects of estradiol on HIF-1α expression and trophoblast differentiation in first trimester villous explant cultures
por: Cho, Geum Joon, et al.
Publicado: (2018)

Trophoblast-Specific Expression of Hif-1α Results in Preeclampsia-Like Symptoms and Fetal Growth Restriction
por: Albers, Renee E., et al.
Publicado: (2019)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro
por: Wang, Mengdong, et al.
Publicado: (2023)

VBP1 negatively regulates CHIP and selectively inhibits the activity of hypoxia-inducible factor (HIF)-1α but not HIF-2α
por: Yue, Yiming, et al.
Publicado: (2023)

HIF1α-dependent mitophagy facilitates cardiomyoblast differentiation
por: Zhao, Jin-Feng, et al.
Publicado: (2020)

Twin Resemblance in Muscle HIF-1α Responses to Hypoxia and Exercise
por: Van Thienen, Ruud, et al.
Publicado: (2017)

HIF-1α contributes to hypoxia adaptation of the naked mole rat
por: Xiao, Bang, et al.
Publicado: (2017)

HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma
por: Valladares, Katherine Julissa Palma, et al.
Publicado: (2021)

Role of hypoxia inducible factor HIF-1α in heart valves
por: Georgy, Mark, et al.
Publicado: (2023)

Transcription-Based Multidimensional Regulation of Fatty Acid Metabolism by HIF1α in Renal Tubules
por: Li, Wenju, et al.
Publicado: (2021)

Metformin suppresses hypoxia-induced migration via the HIF-1α/VEGF pathway in gallbladder cancer in vitro and in vivo
por: Ye, Jianwen, et al.
Publicado: (2019)

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
por: Cui, Chun-Ping, et al.
Publicado: (2017)

Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis
por: Yudoh, Kazuo, et al.
Publicado: (2005)

Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function
por: Knowles, Helen J.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i3ffd6lsasrjimftn3lh49ebuk