Critical role for arginase 2 in obesity-associated pancreatic cancer

Obesity is an established risk factor for pancreatic ductal adenocarcinoma (PDA). Despite recent identification of metabolic alterations in this lethal malignancy, the metabolic dependencies of obesity-associated PDA remain unknown. Here we show that obesity-driven PDA exhibits accelerated growth an...

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Detalles Bibliográficos
Autores principales: Zaytouni, Tamara, Tsai, Pei-Yun, Hitchcock, Daniel S., DuBois, Cory D., Freinkman, Elizaveta, Lin, Lin, Morales-Oyarvide, Vicente, Lenehan, Patrick J., Wolpin, Brian M., Mino-Kenudson, Mari, Torres, Eduardo M., Stylopoulos, Nicholas, Clish, Clary B., Kalaany, Nada Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556090/
https://www.ncbi.nlm.nih.gov/pubmed/28808255
http://dx.doi.org/10.1038/s41467-017-00331-y

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