Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2)

Structural technologies are an essential component in the design of precision therapeutics. Precision medicine entails the development of therapeutics directed toward a designated target protein, with the goal to deliver the right drug to the right patient at the right time. In the field of oncology...

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Detalles Bibliográficos
Autores principales: Anderson, Lissa C., Håkansson, Maria, Walse, Björn, Nilsson, Carol L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Focus: Using Electrons and Radical Chemistry to Characterize Biological Molecules: Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556139/
https://www.ncbi.nlm.nih.gov/pubmed/28681360
http://dx.doi.org/10.1007/s13361-017-1705-0

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