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The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients

BACKGROUND: In evaluation of craniosynostosis patients in terms of neurodevelopmental delay, positron emission tomography computed tomography (PET-CT) scan can be used to assess brain abnormalities through glucose metabolism. We aimed to determine the unnecessity of PET-CT in this study. METHODS: Th...

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Autores principales: Yang, Chae Eun, Park, Eun Kyung, Lee, Myung Chul, Shim, Kyu Won, Kim, Yong Oock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Cleft Palate-Craniofacial Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556738/
https://www.ncbi.nlm.nih.gov/pubmed/28913298
http://dx.doi.org/10.7181/acfs.2017.18.1.21
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author Yang, Chae Eun
Park, Eun Kyung
Lee, Myung Chul
Shim, Kyu Won
Kim, Yong Oock
author_facet Yang, Chae Eun
Park, Eun Kyung
Lee, Myung Chul
Shim, Kyu Won
Kim, Yong Oock
author_sort Yang, Chae Eun
collection PubMed
description BACKGROUND: In evaluation of craniosynostosis patients in terms of neurodevelopmental delay, positron emission tomography computed tomography (PET-CT) scan can be used to assess brain abnormalities through glucose metabolism. We aimed to determine the unnecessity of PET-CT in this study. METHODS: Thirty-eight patients diagnosed with craniosynostosis who underwent distraction osteogenesis from October, 2010 to November, 2013 were reviewed. Magnetic resonance imaging (MRI) and PET-CT scan were carried out for evaluation of the brain structure and function, whereas X-ray and CT scan were taken for evaluation of the skull. RESULTS: Nine patients reported abnormal MRI findings which were not significant, and five patients showed local problem on brain on PET-CT scan. No correlation was found among them. CONCLUSION: PET-CT evaluation of possible abnormal brain findings do not affect surgical planning or require additional therapy. Preoperative PET-CT scan is not the essential study to get any etiologic information of the disease consequences or to establish the treatment plan.
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spelling pubmed-55567382017-09-14 The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients Yang, Chae Eun Park, Eun Kyung Lee, Myung Chul Shim, Kyu Won Kim, Yong Oock Arch Craniofac Surg Original Article BACKGROUND: In evaluation of craniosynostosis patients in terms of neurodevelopmental delay, positron emission tomography computed tomography (PET-CT) scan can be used to assess brain abnormalities through glucose metabolism. We aimed to determine the unnecessity of PET-CT in this study. METHODS: Thirty-eight patients diagnosed with craniosynostosis who underwent distraction osteogenesis from October, 2010 to November, 2013 were reviewed. Magnetic resonance imaging (MRI) and PET-CT scan were carried out for evaluation of the brain structure and function, whereas X-ray and CT scan were taken for evaluation of the skull. RESULTS: Nine patients reported abnormal MRI findings which were not significant, and five patients showed local problem on brain on PET-CT scan. No correlation was found among them. CONCLUSION: PET-CT evaluation of possible abnormal brain findings do not affect surgical planning or require additional therapy. Preoperative PET-CT scan is not the essential study to get any etiologic information of the disease consequences or to establish the treatment plan. The Korean Cleft Palate-Craniofacial Association 2017-03 2017-03-25 /pmc/articles/PMC5556738/ /pubmed/28913298 http://dx.doi.org/10.7181/acfs.2017.18.1.21 Text en Copyright © 2017 The Korean Cleft Palate-Craniofacial Association http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yang, Chae Eun
Park, Eun Kyung
Lee, Myung Chul
Shim, Kyu Won
Kim, Yong Oock
The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients
title The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients
title_full The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients
title_fullStr The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients
title_full_unstemmed The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients
title_short The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients
title_sort unnecessity of positron emission tomography computed tomography in the etiologic evaluation of neurodevelopmental delay in craniosynostosis patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556738/
https://www.ncbi.nlm.nih.gov/pubmed/28913298
http://dx.doi.org/10.7181/acfs.2017.18.1.21
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