An Ensemble-Based Protocol for the Computational Prediction of Helix–Helix Interactions in G Protein-Coupled Receptors using Coarse-Grained Molecular Dynamics

[Image: see text] The accurate identification of the specific points of interaction between G protein-coupled receptor (GPCR) oligomers is essential for the design of receptor ligands targeting oligomeric receptor targets. A coarse-grained molecular dynamics computer simulation approach would provid...

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Detalles Bibliográficos
Autores principales: Altwaijry, Nojood A., Baron, Michael, Wright, David W., Coveney, Peter V., Townsend-Nicholson, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557214/
https://www.ncbi.nlm.nih.gov/pubmed/28383913
http://dx.doi.org/10.1021/acs.jctc.6b01246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557214/
https://www.ncbi.nlm.nih.gov/pubmed/28383913
http://dx.doi.org/10.1021/acs.jctc.6b01246

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