Blocking IL-10 signalling at the time of immunization does not increase unwanted side effects in mice

BACKGROUND: Cancer therapeutic vaccine induced cytotoxic T cell (CTL) responses are pivotal for the killing of tumour cells. Blocking interleukin 10 (IL-10) signalling at the time of immunization increases vaccine induced CTL responses and improves prevention of tumour growth in animal models compar...

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Detalles Bibliográficos
Autores principales: Ni, Guoying, Liao, Zaowen, Chen, Shu, Wang, Tianfang, Yuan, Jianwei, Pan, Xuan, Mounsey, Kate, Cavezza, Shelley, Liu, Xiaosong, Wei, Ming Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557397/
https://www.ncbi.nlm.nih.gov/pubmed/28810829
http://dx.doi.org/10.1186/s12865-017-0224-x

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