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Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition
BACKGROUND: During cancer progression, epithelial cancer cells can be reprogrammed into mesenchymal-like cells with increased migratory potential through the process of epithelial-mesenchymal transition (EMT), representing an essential step of tumor progression towards metastatic state. AGR2 protein...
Autores principales: | Sommerova, Lucia, Ondrouskova, Eva, Vojtesek, Borivoj, Hrstka, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557473/ https://www.ncbi.nlm.nih.gov/pubmed/28810836 http://dx.doi.org/10.1186/s12885-017-3537-5 |
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