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Natural reversal of pulmonary vascular remodeling and right ventricular remodeling in SU5416/hypoxia-treated Sprague-Dawley rats

AIMS: Pulmonary arterial hypertension (PAH) is a lethal disease and improved therapeutic strategies are needed. Increased pulmonary arterial pressure, due to vasoconstriction and vascular remodeling, causes right ventricle (RV) failure and death in patients. The treatment of Sprague-Dawley rats with...

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Detalles Bibliográficos
Autores principales:	Zungu-Edmondson, Makhosazane, Shults, Nataliia V., Melnyk, Oleksiy, Suzuki, Yuichiro J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557492/ https://www.ncbi.nlm.nih.gov/pubmed/28809956 http://dx.doi.org/10.1371/journal.pone.0182551

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