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Mesenchymal stromal cells ameliorate oxidative stress-induced islet endothelium apoptosis and functional impairment via Wnt4-β-catenin signaling

BACKGROUND: Islet dysfunction and destruction are the common cause for both type 1 and type 2 diabetes mellitus (T2DM). The islets of Langerhans are highly vascularized miniorgans, and preserving the structural integrity and full function of the microvascular endothelium is vital for protecting the...

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Detalles Bibliográficos
Autores principales:	Wang, Lingshu, Qing, Li, Liu, He, Liu, Na, Qiao, Jingting, Cui, Chen, He, Tianyi, Zhao, Ruxing, Liu, Fuqiang, Yan, Fei, Wang, Chuan, Liang, Kai, Guo, Xinghong, Shen, Ying H., Hou, Xinguo, Chen, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557510/ https://www.ncbi.nlm.nih.gov/pubmed/28807051 http://dx.doi.org/10.1186/s13287-017-0640-0

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