Structure-function analyses of metal-binding sites of HypA reveal residues important for hydrogenase maturation in Helicobacter pylori

The nickel-containing enzymes of Helicobacter pylori, urease and hydrogenase, are essential for efficient colonization in the human stomach. The insertion of nickel into urease and hydrogenase is mediated by the accessory protein HypA. HypA contains an N-terminal nickel-binding site and a dynamic st...

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Detalles Bibliográficos
Autores principales: Blum, Faith C., Hu, Heidi Q., Servetas, Stephanie L., Benoit, Stéphane L., Maier, Robert J., Maroney, Michael J., Merrell, D. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557546/
https://www.ncbi.nlm.nih.gov/pubmed/28809946
http://dx.doi.org/10.1371/journal.pone.0183260

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