Epigenetic reprogramming converts human Wharton’s jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators

BACKGROUND: Lineage commitment of mesenchymal stem cells (MSCs) to cardiac differentiation is controlled by transcription factors that are regulated by epigenetic events, mainly histone deacetylation and promoter DNA methylation. Here, we studied the differentiation of human Wharton’s jelly MSCs (WJ...

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Detalles Bibliográficos
Autores principales: Bhuvanalakshmi, G., Arfuso, Frank, Kumar, Alan Prem, Dharmarajan, Arun, Warrier, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557557/
https://www.ncbi.nlm.nih.gov/pubmed/28807014
http://dx.doi.org/10.1186/s13287-017-0638-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557557/
https://www.ncbi.nlm.nih.gov/pubmed/28807014
http://dx.doi.org/10.1186/s13287-017-0638-7

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