Selepressin, a novel selective vasopressin V(1A) agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients

BACKGROUND: Vasopressin is widely used for vasopressor support in septic shock patients, but experimental evidence suggests that selective V(1A) agonists are superior. The initial pharmacodynamic effects, pharmacokinetics, and safety of selepressin, a novel V(1A)-selective vasopressin analogue, was...

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Detalles Bibliográficos
Autores principales: Russell, James A., Vincent, Jean-Louis, Kjølbye, Anne Louise, Olsson, Håkan, Blemings, Allan, Spapen, Herbert, Carl, Peder, Laterre, Pierre-Francois, Grundemar, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557574/
https://www.ncbi.nlm.nih.gov/pubmed/28807037
http://dx.doi.org/10.1186/s13054-017-1798-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557574/
https://www.ncbi.nlm.nih.gov/pubmed/28807037
http://dx.doi.org/10.1186/s13054-017-1798-7

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