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A parallel metaheuristic for large mixed-integer dynamic optimization problems, with applications in computational biology
BACKGROUND: We consider a general class of global optimization problems dealing with nonlinear dynamic models. Although this class is relevant to many areas of science and engineering, here we are interested in applying this framework to the reverse engineering problem in computational systems biolo...
Autores principales: | Penas, David R., Henriques, David, González, Patricia, Doallo, Ramón, Saez-Rodriguez, Julio, Banga, Julio R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557587/ https://www.ncbi.nlm.nih.gov/pubmed/28813442 http://dx.doi.org/10.1371/journal.pone.0182186 |
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