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Deletion of Cytoplasmic Double-Stranded RNA Sensors Does Not Uncover Viral Small Interfering RNA Production in Human Cells

Antiviral immunity in insects and plants is mediated by the RNA interference (RNAi) pathway in which viral long double-stranded RNA (dsRNA) is processed into small interfering RNAs (siRNAs) by Dicer enzymes. Although this pathway is evolutionarily conserved, its involvement in antiviral defense in m...

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Detalles Bibliográficos
Autores principales:	Schuster, Susan, Tholen, Lotte E., Overheul, Gijs J., van Kuppeveld, Frank J. M., van Rij, Ronald P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Observation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557678/ https://www.ncbi.nlm.nih.gov/pubmed/28815217 http://dx.doi.org/10.1128/mSphere.00333-17

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