Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation

Atherosclerosis impacts arteries where disturbed blood flow renders the endothelium susceptible to inflammation. Cytokine activation of endothelial cells (EC) upregulates VCAM-1 receptors that target monocyte recruitment to atherosusceptible regions. Endoplasmic reticulum (ER) stress elicits EC dysr...

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Detalles Bibliográficos
Autores principales: Bailey, Keith A., Haj, Fawaz G., Simon, Scott I., Passerini, Anthony G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557756/
https://www.ncbi.nlm.nih.gov/pubmed/28811527
http://dx.doi.org/10.1038/s41598-017-08417-9

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