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Negative Correlation between Circulating CD4(+)FOXP3(+)CD127(−) Regulatory T Cells and Subsequent Antibody Responses to Infant Measles Vaccine but Not Diphtheria–Tetanus–Pertussis Vaccine Implies a Regulatory Role
Regulatory T cells (Tregs) play a key homeostatic role by suppressing immune responses. They have been targeted in mouse and human cancer studies to improve vaccine immunogenicity and tumor clearance. A number of commercially available drugs and experimental vaccine adjuvants have been shown to targ...
Autores principales: | Ndure, Jorjoh, Noho-Konteh, Fatou, Adetifa, Jane U., Cox, Momodou, Barker, Francis, Le, My Thanh, Sanyang, Lady C., Drammeh, Adboulie, Whittle, Hilton C., Clarke, Ed, Plebanski, Magdalena, Rowland-Jones, Sarah L., Flanagan, Katie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557771/ https://www.ncbi.nlm.nih.gov/pubmed/28855899 http://dx.doi.org/10.3389/fimmu.2017.00921 |
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