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Histone deacetylase 6 (HDAC6) is an essential factor for oocyte maturation and asymmetric division in mice
Tubastatin A (Tub-A), a highly selective histone deacetylase 6 (HDAC6) inhibitor, has been widely used as a cytotoxic anticancer agent, or for the treatment of patients with asthma. However, the potential toxicity of Tub-A on oocyte maturation and asymmetric division is still unclear. Therefore, the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557833/ https://www.ncbi.nlm.nih.gov/pubmed/28811599 http://dx.doi.org/10.1038/s41598-017-08650-2 |