Deregulation of ZPR1 causes respiratory failure in spinal muscular atrophy

Spinal muscular atrophy (SMA) is caused by the low levels of survival motor neuron (SMN) protein and is characterized by motor neuron degeneration and muscle atrophy. Respiratory failure causes death in SMA but the underlying molecular mechanism is unknown. The zinc finger protein ZPR1 interacts wit...

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Detalles Bibliográficos
Autores principales: Genabai, Naresh K., Kannan, Annapoorna, Ahmad, Saif, Jiang, Xiaoting, Bhatia, Kanchan, Gangwani, Laxman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557895/
https://www.ncbi.nlm.nih.gov/pubmed/28811488
http://dx.doi.org/10.1038/s41598-017-07603-z

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