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Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism

Major complications of heart transplantation include graft rejection, infection, graft arteriosclerosis, malignancy, and drug toxicity. Among these complications, infections and thrombophilic disorders are of particular interest owing to their major contribution to morbidity and mortality among hear...

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Detalles Bibliográficos
Autores principales: Mirhosseini, Seyed Mohsen, Sanjari Moghaddam, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences, 2006- 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558062/
https://www.ncbi.nlm.nih.gov/pubmed/28828026
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author Mirhosseini, Seyed Mohsen
Sanjari Moghaddam, Ali
author_facet Mirhosseini, Seyed Mohsen
Sanjari Moghaddam, Ali
author_sort Mirhosseini, Seyed Mohsen
collection PubMed
description Major complications of heart transplantation include graft rejection, infection, graft arteriosclerosis, malignancy, and drug toxicity. Among these complications, infections and thrombophilic disorders are of particular interest owing to their major contribution to morbidity and mortality among heart transplantation patients. Thrombophilic disorders are caused by imbalance between hypercoagulation and fibrinolytic states. In this report, we describe a 43-year-old man who had unusual complications of heart transplantation. We presume that the unusual postoperative complications of the patient might have been caused by a faulty surgical procedure, improper use of anticoagulant agents, and incomplete prophylaxis for infections. During the postoperative period, the patient suffered arterial obstruction three times, for which he underwent clot removal via embolectomy. In addition to arterial obstruction, the patient had a mobile mass in the left atrium that was removed by open cardiac surgery. The frozen sample of the cardiac mass was positive for Acinetobacter baumannii. After 7 days of observation in the hospital and proper antibiotic regimen, the patient was sent home with no additional complaints and normal physical examination. We conclude that in heart transplantation patients, the precise performance of the surgical procedure, postoperative care, and early removal of the embolus might reduce morbidities and mortality due to thrombophilic disorders.
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spelling pubmed-55580622017-08-21 Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism Mirhosseini, Seyed Mohsen Sanjari Moghaddam, Ali J Tehran Heart Cent Case Report Major complications of heart transplantation include graft rejection, infection, graft arteriosclerosis, malignancy, and drug toxicity. Among these complications, infections and thrombophilic disorders are of particular interest owing to their major contribution to morbidity and mortality among heart transplantation patients. Thrombophilic disorders are caused by imbalance between hypercoagulation and fibrinolytic states. In this report, we describe a 43-year-old man who had unusual complications of heart transplantation. We presume that the unusual postoperative complications of the patient might have been caused by a faulty surgical procedure, improper use of anticoagulant agents, and incomplete prophylaxis for infections. During the postoperative period, the patient suffered arterial obstruction three times, for which he underwent clot removal via embolectomy. In addition to arterial obstruction, the patient had a mobile mass in the left atrium that was removed by open cardiac surgery. The frozen sample of the cardiac mass was positive for Acinetobacter baumannii. After 7 days of observation in the hospital and proper antibiotic regimen, the patient was sent home with no additional complaints and normal physical examination. We conclude that in heart transplantation patients, the precise performance of the surgical procedure, postoperative care, and early removal of the embolus might reduce morbidities and mortality due to thrombophilic disorders. Tehran University of Medical Sciences, 2006- 2017-04 /pmc/articles/PMC5558062/ /pubmed/28828026 Text en Copyright © 2015 Tehran Heart Center, Tehran University of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mirhosseini, Seyed Mohsen
Sanjari Moghaddam, Ali
Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism
title Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism
title_full Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism
title_fullStr Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism
title_full_unstemmed Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism
title_short Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism
title_sort limb ischemia after heart transplantation: an unusual case of tissue embolism
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558062/
https://www.ncbi.nlm.nih.gov/pubmed/28828026
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