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The Diagnostic Accuracy of Conventional Forceps Biopsy Compared to ESD
OBJECTIVE: conventional forceps biopsy (CFB) is the most popular way to screen for gastric epithelial neoplasia (GEN). Our study aimed to compare the diagnostic accuracy between conventional forceps biopsy and endoscopic submucosal dissection (ESD). METHODS: 105 patients diagnosed GEN finally undert...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter Open
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558105/ https://www.ncbi.nlm.nih.gov/pubmed/28828409 http://dx.doi.org/10.1515/med-2017-0039 |
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author | Wu, Shimin Zhu, Xinjian Xiang, Lijuan Chen, Jianqiang Chen, Chunxiao |
author_facet | Wu, Shimin Zhu, Xinjian Xiang, Lijuan Chen, Jianqiang Chen, Chunxiao |
author_sort | Wu, Shimin |
collection | PubMed |
description | OBJECTIVE: conventional forceps biopsy (CFB) is the most popular way to screen for gastric epithelial neoplasia (GEN). Our study aimed to compare the diagnostic accuracy between conventional forceps biopsy and endoscopic submucosal dissection (ESD). METHODS: 105 patients diagnosed GEN finally undertook ESD in our hospital were enrolled. We retrospectively assessed the characteristics of pathological results of CFB and ESD. RESULTS: The overall pathologic concordance rate between the CFB and ESD specimens was 68.57%. 55 cases of CFB maintained low-grade intraepithelial neoplasia (LGIN) under ESD,18 cases (23.1%) diagnosis for high-grade intraepithelial neoplasia (HGIN), 5 cases (6.4%) diagnosis for cancer. Moreover, 10 cases of CFB maintained HGIN under ESD. Lesions with surface hyperemia (44.4% vs. 27.54%) or surface ulcer (57.14% vs.26.76%) were more likely to cancerate (P<0.05). CONCLUSION: endoscopic biopsy in the diagnosis of low-grade intraepithelial neoplasia, may exist or progression to high-grade intraepithelial neoplasia, some may have cancer, should take active treatment measures. |
format | Online Article Text |
id | pubmed-5558105 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | De Gruyter Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-55581052017-08-21 The Diagnostic Accuracy of Conventional Forceps Biopsy Compared to ESD Wu, Shimin Zhu, Xinjian Xiang, Lijuan Chen, Jianqiang Chen, Chunxiao Open Med (Wars) Regular Articles OBJECTIVE: conventional forceps biopsy (CFB) is the most popular way to screen for gastric epithelial neoplasia (GEN). Our study aimed to compare the diagnostic accuracy between conventional forceps biopsy and endoscopic submucosal dissection (ESD). METHODS: 105 patients diagnosed GEN finally undertook ESD in our hospital were enrolled. We retrospectively assessed the characteristics of pathological results of CFB and ESD. RESULTS: The overall pathologic concordance rate between the CFB and ESD specimens was 68.57%. 55 cases of CFB maintained low-grade intraepithelial neoplasia (LGIN) under ESD,18 cases (23.1%) diagnosis for high-grade intraepithelial neoplasia (HGIN), 5 cases (6.4%) diagnosis for cancer. Moreover, 10 cases of CFB maintained HGIN under ESD. Lesions with surface hyperemia (44.4% vs. 27.54%) or surface ulcer (57.14% vs.26.76%) were more likely to cancerate (P<0.05). CONCLUSION: endoscopic biopsy in the diagnosis of low-grade intraepithelial neoplasia, may exist or progression to high-grade intraepithelial neoplasia, some may have cancer, should take active treatment measures. De Gruyter Open 2017-08-12 /pmc/articles/PMC5558105/ /pubmed/28828409 http://dx.doi.org/10.1515/med-2017-0039 Text en © 2017 Shimin Wu et al. http://creativecommons.org/licenses/by-nc-nd/3.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. |
spellingShingle | Regular Articles Wu, Shimin Zhu, Xinjian Xiang, Lijuan Chen, Jianqiang Chen, Chunxiao The Diagnostic Accuracy of Conventional Forceps Biopsy Compared to ESD |
title | The Diagnostic Accuracy of Conventional Forceps Biopsy Compared to ESD |
title_full | The Diagnostic Accuracy of Conventional Forceps Biopsy Compared to ESD |
title_fullStr | The Diagnostic Accuracy of Conventional Forceps Biopsy Compared to ESD |
title_full_unstemmed | The Diagnostic Accuracy of Conventional Forceps Biopsy Compared to ESD |
title_short | The Diagnostic Accuracy of Conventional Forceps Biopsy Compared to ESD |
title_sort | diagnostic accuracy of conventional forceps biopsy compared to esd |
topic | Regular Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558105/ https://www.ncbi.nlm.nih.gov/pubmed/28828409 http://dx.doi.org/10.1515/med-2017-0039 |
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