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Pancreatitis: Preventing catastrophic haemorrhage

Pancreatitis represents nearly 3% of acute admissions to general surgery in United Kingdom hospitals and has a mortality of around 1%-7% which increases to around 10%-18% in patients with severe pancreatitis. Patients at greatest risk were those identified to have infected pancreatic necrosis and/or...

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Autores principales: Evans, Richard PT, Mourad, Moustafa Mabrouk, Pall, Gunraj, Fisher, Simon G, Bramhall, Simon R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558110/
https://www.ncbi.nlm.nih.gov/pubmed/28852306
http://dx.doi.org/10.3748/wjg.v23.i30.5460
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author Evans, Richard PT
Mourad, Moustafa Mabrouk
Pall, Gunraj
Fisher, Simon G
Bramhall, Simon R
author_facet Evans, Richard PT
Mourad, Moustafa Mabrouk
Pall, Gunraj
Fisher, Simon G
Bramhall, Simon R
author_sort Evans, Richard PT
collection PubMed
description Pancreatitis represents nearly 3% of acute admissions to general surgery in United Kingdom hospitals and has a mortality of around 1%-7% which increases to around 10%-18% in patients with severe pancreatitis. Patients at greatest risk were those identified to have infected pancreatic necrosis and/or organ failure. This review seeks to highlight the potential vascular complications associated with pancreatitis that despite being relatively uncommon are associated with mortality in the region of 34%-52%. We examine the current evidence base to determine the most appropriate method by which to image and treat pseudo-aneurysms that arise as the result of acute and chronic inflammation of pancreas. We identify how early recognition of the presence of a pseudo-aneurysm can facilitate expedited care in an expert centre of a complex pathology that may require angiographic, percutaneous, endoscopic or surgical intervention to prevent catastrophic haemorrhage.
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spelling pubmed-55581102017-08-29 Pancreatitis: Preventing catastrophic haemorrhage Evans, Richard PT Mourad, Moustafa Mabrouk Pall, Gunraj Fisher, Simon G Bramhall, Simon R World J Gastroenterol Review Pancreatitis represents nearly 3% of acute admissions to general surgery in United Kingdom hospitals and has a mortality of around 1%-7% which increases to around 10%-18% in patients with severe pancreatitis. Patients at greatest risk were those identified to have infected pancreatic necrosis and/or organ failure. This review seeks to highlight the potential vascular complications associated with pancreatitis that despite being relatively uncommon are associated with mortality in the region of 34%-52%. We examine the current evidence base to determine the most appropriate method by which to image and treat pseudo-aneurysms that arise as the result of acute and chronic inflammation of pancreas. We identify how early recognition of the presence of a pseudo-aneurysm can facilitate expedited care in an expert centre of a complex pathology that may require angiographic, percutaneous, endoscopic or surgical intervention to prevent catastrophic haemorrhage. Baishideng Publishing Group Inc 2017-08-14 2017-08-14 /pmc/articles/PMC5558110/ /pubmed/28852306 http://dx.doi.org/10.3748/wjg.v23.i30.5460 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Review
Evans, Richard PT
Mourad, Moustafa Mabrouk
Pall, Gunraj
Fisher, Simon G
Bramhall, Simon R
Pancreatitis: Preventing catastrophic haemorrhage
title Pancreatitis: Preventing catastrophic haemorrhage
title_full Pancreatitis: Preventing catastrophic haemorrhage
title_fullStr Pancreatitis: Preventing catastrophic haemorrhage
title_full_unstemmed Pancreatitis: Preventing catastrophic haemorrhage
title_short Pancreatitis: Preventing catastrophic haemorrhage
title_sort pancreatitis: preventing catastrophic haemorrhage
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558110/
https://www.ncbi.nlm.nih.gov/pubmed/28852306
http://dx.doi.org/10.3748/wjg.v23.i30.5460
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