Cargando…
Leveraging network analytics to infer patient syndrome and identify causal genes in rare disease cases
BACKGROUND: Next-generation sequencing is widely used to identify disease-causing variants in patients with rare genetic disorders. Identifying those variants from whole-genome or exome data can be both scientifically challenging and time consuming. A significant amount of time is spent on variant a...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558185/ https://www.ncbi.nlm.nih.gov/pubmed/28812537 http://dx.doi.org/10.1186/s12864-017-3910-4 |