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Heat shock protein 72 expression allows permissive replication of oncolytic adenovirus dl1520 (ONYX-015) in rat glioblastoma cells

In this study we have made novel observations with regards to potentiation of the tumoricidal activity of the oncolytic adenovirus, dl1520 (ONYX-015) in rat glioblastoma cell lines expressing heat shock protein 72 (HSP72) due to permissive virus replication. ONYX-015 is a conditionally replicating a...

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Detalles Bibliográficos
Autores principales: Madara, Jonathan, Krewet, James A, Shah, Maulik
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555846/
https://www.ncbi.nlm.nih.gov/pubmed/15762988
http://dx.doi.org/10.1186/1476-4598-4-12