Immunogenetics of Hashimoto's thyroiditis

Hashimoto's thyroiditis (HT) is an organ-specific T-cell mediated disease. It is a complex disease, with a strong genetic component. To date, significant progress has been made towards the identification and functional characterization of HT susceptibility genes. In this review, we will summari...

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Detalles Bibliográficos
Autor principal: Chistiakov, Dimitry A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555850/
https://www.ncbi.nlm.nih.gov/pubmed/15762980
http://dx.doi.org/10.1186/1740-2557-2-1
Descripción
Sumario:Hashimoto's thyroiditis (HT) is an organ-specific T-cell mediated disease. It is a complex disease, with a strong genetic component. To date, significant progress has been made towards the identification and functional characterization of HT susceptibility genes. In this review, we will summarize the recent advances in our understanding of the genetic input to the pathogenesis of HT.

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