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β2-Adrenergic Receptor-Mediated HIF-1α Upregulation Mediates Blood Brain Barrier Damage in Acute Cerebral Ischemia

Disruption of the blood brain barrier (BBB) within the thrombolytic time window is an antecedent event to intracerebral hemorrhage in ischemic stroke. Our recent studies showed that 2-h cerebral ischemia induced BBB damage in non-infarcted area and secreted matrix metalloproteinase-2 (MMP-2) account...

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Detalles Bibliográficos
Autores principales:	Sun, Yanyun, Chen, Xi, Zhang, Xinyu, Shen, Xianzhi, Wang, Mengwei, Wang, Xiaona, Liu, Wen-Cao, Liu, Chun-Feng, Liu, Jie, Liu, Wenlan, Jin, Xinchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558520/ https://www.ncbi.nlm.nih.gov/pubmed/28855859 http://dx.doi.org/10.3389/fnmol.2017.00257

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