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NRAS-mutant melanoma: current challenges and future prospect

Melanoma is one of the most common cutaneous cancers worldwide. Activating mutations in RAS oncogenes are found in a third of all human cancers and NRAS mutations are found in 15%–20% of melanomas. The NRAS-mutant subset of melanoma is more aggressive and associated with poorer outcomes, compared to...

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Detalles Bibliográficos
Autores principales: Muñoz-Couselo, Eva, Adelantado, Ester Zamora, Ortiz, Carolina, García, Jesús Soberino, Perez-Garcia, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558581/
https://www.ncbi.nlm.nih.gov/pubmed/28860801
http://dx.doi.org/10.2147/OTT.S117121