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The impact of age and gut microbiota on Th17 and Tfh cells in K/BxN autoimmune arthritis

BACKGROUND: Age is an important risk factor for rheumatoid arthritis (RA), which often develops in middle age. However, how age-associated changes in immunity impact RA is poorly understood. Gut microbiota are known to be involved in the pathogenesis of RA, but the effects of microbiota in older sub...

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Detalles Bibliográficos
Autores principales: Teng, Fei, Felix, Krysta M., Bradley, C. Pierce, Naskar, Debdut, Ma, Heqing, Raslan, Walid A., Wu, Hsin-Jung Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558662/
https://www.ncbi.nlm.nih.gov/pubmed/28810929
http://dx.doi.org/10.1186/s13075-017-1398-6