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LIM kinase 1 interacts with myosin-9 and alpha-actinin-4 and promotes colorectal cancer progression

BACKGROUND: LIM kinase 1 (LIMK1) is a key regulator of the cytoskeletal organisation involved in cell proliferation and migration. Even though LIMK1 is frequently dysregulated in epithelial cancers, the role and mechanisms of LIMK1 in colorectal cancer (CRC) remains unclear. METHODS: Immunohistochem...

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Detalles Bibliográficos
Autores principales: Liao, Qing, Li, Rui, Zhou, Rui, Pan, Zhihua, Xu, Lijun, Ding, Yanqing, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558682/
https://www.ncbi.nlm.nih.gov/pubmed/28664914
http://dx.doi.org/10.1038/bjc.2017.193