TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy

BACKGROUND: Tumour-specific radiosensitising treatments may enhance the efficacy of radiotherapy without exacerbating side effects. In this study we determined the radiation response following depletion or inhibition of TOPK, a mitogen-activated protein kinase kinase family Ser/Thr protein kinase th...

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Detalles Bibliográficos
Autores principales: Pirovano, Giacomo, Ashton, Thomas M, Herbert, Katharine J, Bryant, Richard J, Verrill, Clare L, Cerundolo, Lucia, Buffa, Francesca M, Prevo, Remko, Harrap, Iona, Ryan, Anderson J, Macaulay, Valentine, McKenna, William G, Higgins, Geoff S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558685/
https://www.ncbi.nlm.nih.gov/pubmed/28677687
http://dx.doi.org/10.1038/bjc.2017.197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558685/
https://www.ncbi.nlm.nih.gov/pubmed/28677687
http://dx.doi.org/10.1038/bjc.2017.197

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