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Non-invasive prediction of recurrence in bladder cancer by detecting somatic TERT promoter mutations in urine

BACKGROUND: Urothelial bladder cancer (UBC) is characterised by a high risk of recurrence. Patient monitoring is currently based on iterative cystoscopy and on urine cytology with low sensitivity in non-muscle-invasive bladder cancer (NMIBC). Telomerase reverse transcriptase (TERT) is frequently rea...

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Detalles Bibliográficos
Autores principales:	Descotes, Françoise, Kara, Norelyakin, Decaussin-Petrucci, Myriam, Piaton, Eric, Geiguer, Florence, Rodriguez-Lafrasse, Claire, Terrier, Jean E, Lopez, Jonathan, Ruffion, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Genetics & Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558690/ https://www.ncbi.nlm.nih.gov/pubmed/28683471 http://dx.doi.org/10.1038/bjc.2017.210

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