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Archaeal fibrillarin–Nop5 heterodimer 2′-O-methylates RNA independently of the C/D guide RNP particle

Archaeal fibrillarin (aFib) is a well-characterized S-adenosyl methionine (SAM)-dependent RNA 2′-O-methyltransferase that is known to act in a large C/D ribonucleoprotein (RNP) complex together with Nop5 and L7Ae proteins and a box C/D guide RNA. In the reaction, the guide RNA serves to direct the m...

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Detalles Bibliográficos
Autores principales:	Tomkuvienė, Miglė, Ličytė, Janina, Olendraitė, Ingrida, Liutkevičiūtė, Zita, Clouet-d'Orval, Béatrice, Klimašauskas, Saulius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558902/ https://www.ncbi.nlm.nih.gov/pubmed/28576826 http://dx.doi.org/10.1261/rna.059832.116

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