Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma

Telomeres are repetitive DNA sequences at linear chromosome termini, protecting chromosomes against end-to-end fusion and damage, providing chromosomal stability. Telomeres shorten with mitotic cellular division, but are maintained in cells with high proliferative capacity by telomerase. Loss-of-fun...

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Detalles Bibliográficos
Autores principales: Donaires, Flávia S., Scatena, Natália F., Alves-Paiva, Raquel M., Podlevsky, Joshua D., Logeswaran, Dhenugen, Santana, Barbara A., Teixeira, Andreza C., Chen, Julian J.-L., Calado, Rodrigo T., Martinelli, Ana L. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558955/
https://www.ncbi.nlm.nih.gov/pubmed/28813500
http://dx.doi.org/10.1371/journal.pone.0183287

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