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Corrupting the DNA damage response: a critical role for Rad52 in tumor cell survival

The DNA damage response enables cells to survive, maintain genome integrity, and to safeguard the transmission of high-fidelity genetic information. Upon sensing DNA damage, cells respond by activating this multifaceted DNA damage response leading to restoration of the cell, senescence, programmed c...

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Detalles Bibliográficos
Autores principales: Lieberman, Rachel, You, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559167/
https://www.ncbi.nlm.nih.gov/pubmed/28722656
http://dx.doi.org/10.18632/aging.101263