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The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion
Several age-related neurodegenerative disorders are associated with protein misfolding and aggregation of toxic peptides. α-synuclein (α-syn) aggregation and the resulting cytotoxicity is a hallmark of Parkinson's disease (PD) as well as dementia with Lewy bodies. Rising evidence points to olig...
Autores principales: | von Einem, Bjoern, Eschbach, Judith, Kiechle, Martin, Wahler, Anke, Thal, Dietmar R., McLean, Pamela J., Weishaupt, Jochen H., Ludolph, Albert C., von Arnim, Christine A.F., Danzer, Karin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559169/ https://www.ncbi.nlm.nih.gov/pubmed/28722658 http://dx.doi.org/10.18632/aging.101261 |
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