HIF-1–dependent regulation of lifespan in Caenorhabditis elegans by the acyl-CoA–binding protein MAA-1

In yeast, the broadly conserved acyl-CoA–binding protein (ACBP) is a negative regulator of stress resistance and longevity. Here, we have turned to the nematode C. elegans as a model organism in which to determine whether ACBPs play similar roles in multicellular organisms. We systematically inactiv...

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Detalles Bibliográficos
Autores principales: Shamalnasab, Mehrnaz, Dhaoui, Manel, Thondamal, Manjunatha, Harvald, Eva Bang, Færgeman, Nils J., Aguilaniu, Hugo, Fabrizio, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559173/
https://www.ncbi.nlm.nih.gov/pubmed/28758895
http://dx.doi.org/10.18632/aging.101267

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