Cargando…

Aging and calorie restriction regulate the expression of miR-125a-5p and its target genes Stat3, Casp2 and Stard13

Calorie restriction (CR) is a dietary intervention known to delay aging. In order, to understand molecular mechanisms of CR, we analyzed the expression of 983 MicroRNAs (miRNAs) in the liver of female mice after 2 years of 30% CR using micro-array. 16 miRNAs demonstrated significant changes in their...

Descripción completa

Detalles Bibliográficos
Autores principales: Makwana, Kuldeep, Patel, Sonal Arvind, Velingkaar, Nikkhil, Ebron, Jey Sabith, Shukla, Girish C., Kondratov, Roman V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559175/
https://www.ncbi.nlm.nih.gov/pubmed/28783714
http://dx.doi.org/10.18632/aging.101270