Cargando…
Adult-onset obesity is triggered by impaired mitochondrial gene expression
Mitochondrial gene expression is essential for energy production; however, an understanding of how it can influence physiology and metabolism is lacking. Several proteins from the pentatricopeptide repeat (PPR) family are essential for the regulation of mitochondrial gene expression, but the functio...
Autores principales: | Perks, Kara L., Ferreira, Nicola, Richman, Tara R., Ermer, Judith A., Kuznetsova, Irina, Shearwood, Anne-Marie J., Lee, Richard G., Viola, Helena M., Johnstone, Victoria P. A., Matthews, Vance, Hool, Livia C., Rackham, Oliver, Filipovska, Aleksandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559209/ https://www.ncbi.nlm.nih.gov/pubmed/28835921 http://dx.doi.org/10.1126/sciadv.1700677 |
Ejemplares similares
-
Mutation in MRPS34 Compromises Protein Synthesis and Causes Mitochondrial Dysfunction
por: Richman, Tara R., et al.
Publicado: (2015) -
Fidelity of translation initiation is required for coordinated respiratory complex assembly
por: Rudler, Danielle L., et al.
Publicado: (2019) -
Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation
por: Perks, Kara L., et al.
Publicado: (2020) -
Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan
por: Richman, Tara R., et al.
Publicado: (2021) -
Simultaneous processing and degradation of mitochondrial RNAs revealed by circularized RNA sequencing
por: Kuznetsova, Irina, et al.
Publicado: (2017)