Disruption of the structural and functional features of surfactant protein A by acrolein in cigarette smoke

The extent to which defective innate immune responses contribute to chronic obstructive pulmonary disease (COPD) is not fully understood. Pulmonary surfactant protein A (SP-A) plays an important role in regulating innate immunity in the lungs. In this study, we hypothesised that cigarette smoke (CS)...

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Detalles Bibliográficos
Autores principales: Takamiya, Rina, Uchida, Koji, Shibata, Takahiro, Maeno, Toshitaka, Kato, Masaki, Yamaguchi, Yoshiki, Ariki, Shigeru, Hasegawa, Yoshihiro, Saito, Atsushi, Miwa, Soichi, Takahashi, Hiroki, Akaike, Takaaki, Kuroki, Yoshio, Takahashi, Motoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559459/
https://www.ncbi.nlm.nih.gov/pubmed/28814727
http://dx.doi.org/10.1038/s41598-017-08588-5

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