Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities

A new series of phenolic glycoside esters, saccharumoside-B and its analogs (9b-9n, 10) have been synthesized by the Koenigs-Knorr reaction. Antiproliferative activities of the compounds (9b-9n, 10) were evaluated on various cancer cell lines including, MCF-7 breast, HL-60 leukemia, MIA PaCa-2 pancr...

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Detalles Bibliográficos
Autores principales: Rayavarapu, Srinuvasarao, Yarla, Nagendra Sastry, Kadiri, Sunanda Kumari, Bishayee, Anupam, Vidavalur, Siddaiah, Tadikonda, Ramu, Basha, Mahaboob, Pidugu, Vijaya Rao, Dowluru, Kaladhar S. V. G. K., Lakappa, Dhananjaya Bhadrapura, Kamal, Mohammad A., Md Ashraf, Ghulam, Tarasov, Vadim V., Chubarev, Vladimir N., Klochkov, Sergey G., Barreto, George E., Bachurin, Sergey O., Aliev, Gjumrakch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559490/
https://www.ncbi.nlm.nih.gov/pubmed/28814788
http://dx.doi.org/10.1038/s41598-017-05832-w

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