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A Stimulation Function of Synaptotagmin-1 in Ternary SNARE Complex Formation Dependent on Munc18 and Munc13

The Ca(2+) sensor synaptotagmin-1 (Syt1) plays an essential function in synaptic exocytosis. Recently, Syt1 has been implicated in synaptic vesicle priming, a maturation step prior to Ca(2+)-triggered membrane fusion that is believed to involve formation of the ternary SNARE complex and require prim...

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Detalles Bibliográficos
Autores principales: Li, Yun, Wang, Shen, Li, Tianzhi, Zhu, Le, Xu, Yuanyuan, Ma, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559510/
https://www.ncbi.nlm.nih.gov/pubmed/28860966
http://dx.doi.org/10.3389/fnmol.2017.00256