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Drosophila protease ClpXP specifically degrades DmLRPPRC1 controlling mitochondrial mRNA and translation

ClpXP is the major protease in the mitochondrial matrix in eukaryotes, and is well conserved among species. ClpXP is composed of a proteolytic subunit, ClpP, and a chaperone-like subunit, ClpX. Although it has been proposed that ClpXP is required for the mitochondrial unfolded protein response, addi...

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Detalles Bibliográficos
Autores principales: Matsushima, Yuichi, Hirofuji, Yuta, Aihara, Masamune, Yue, Song, Uchiumi, Takeshi, Kaguni, Laurie S., Kang, Dongchon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559520/
https://www.ncbi.nlm.nih.gov/pubmed/28814717
http://dx.doi.org/10.1038/s41598-017-08088-6

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