Genomic Evolution of Breast Cancer Metastasis and Relapse

Patterns of genomic evolution between primary and metastatic breast cancer have not been studied in large numbers, despite patients with metastatic breast cancer having dismal survival. We sequenced whole genomes or a panel of 365 genes on 299 samples from 170 patients with locally relapsed or metas...

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Detalles Bibliográficos
Autores principales: Yates, Lucy R., Knappskog, Stian, Wedge, David, Farmery, James H.R., Gonzalez, Santiago, Martincorena, Inigo, Alexandrov, Ludmil B., Van Loo, Peter, Haugland, Hans Kristian, Lilleng, Peer Kaare, Gundem, Gunes, Gerstung, Moritz, Pappaemmanuil, Elli, Gazinska, Patrycja, Bhosle, Shriram G., Jones, David, Raine, Keiran, Mudie, Laura, Latimer, Calli, Sawyer, Elinor, Desmedt, Christine, Sotiriou, Christos, Stratton, Michael R., Sieuwerts, Anieta M., Lynch, Andy G., Martens, John W., Richardson, Andrea L., Tutt, Andrew, Lønning, Per Eystein, Campbell, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559645/
https://www.ncbi.nlm.nih.gov/pubmed/28810143
http://dx.doi.org/10.1016/j.ccell.2017.07.005

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