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Delayed Cryptochrome Degradation Asymmetrically Alters the Daily Rhythm in Suprachiasmatic Clock Neuron Excitability

Suprachiasmatic nuclei (SCN) neurons contain an intracellular molecular circadian clock and the Cryptochromes (CRY1/2), key transcriptional repressors of this molecular apparatus, are subject to post-translational modification through ubiquitination and targeting for proteosomal degradation by the u...

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Detalles Bibliográficos
Autores principales:	Wegner, Sven, Belle, Mino D.C., Hughes, Alun T.L., Diekman, Casey O., Piggins, Hugh D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559760/ https://www.ncbi.nlm.nih.gov/pubmed/28698388 http://dx.doi.org/10.1523/JNEUROSCI.0691-17.2017

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