Monoallelic characteristic-bearing heterozygous L1053X in BRCA2 gene among Sudanese women with breast cancer

BACKGROUND: Breast cancer (BC) is the most common type of cancer in women. Among many risk factors of BC, mutations in BRCA2 gene were found to be the primary cause in 5–10% of cases. The majority of deleterious mutations are frameshift or nonsense mutations. Most of the reported BRCA2 mutations are...

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Detalles Bibliográficos
Autores principales: Elimam, Alsmawal A., Aabdein, Mohamed Elmogtba Mouaweia Mohamed, Eldeen, Mohamed El-Fatih Moly, Altayb, Hisham N., Taha, Mohamed Adel, Nimir, Mohammed N., Dafaalla, Mohamed D., Alfaki, Musaab M., Abdelrahim, Mohamed A., Abdalla, Abdelmohaymin A., Mohammed, Musab I., Ellaithi, Mona, Hamid, Muzamil Mahdi Abdel, Hassan, Mohamed Ahmed Salih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559773/
https://www.ncbi.nlm.nih.gov/pubmed/28814288
http://dx.doi.org/10.1186/s12881-017-0448-x

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