Stable inheritance of DNA methylation allows creation of epigenotype maps and the study of epiallele inheritance patterns in the absence of genetic variation

BACKGROUND: Differences in DNA methylation can arise as epialleles, which are loci that differ in chromatin state and are inherited over generations. Epialleles offer an additional source of variation that can affect phenotypic diversity beyond changes to nucleotide sequence. Previous research has l...

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Detalles Bibliográficos
Autores principales: Hofmeister, Brigitte T., Lee, Kevin, Rohr, Nicholas A., Hall, David W., Schmitz, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559844/
https://www.ncbi.nlm.nih.gov/pubmed/28814343
http://dx.doi.org/10.1186/s13059-017-1288-x

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