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Randomized study comparing full dose monotherapy (S-1 followed by irinotecan) and reduced dose combination therapy (S-1/oxaliplatin followed by S-1/irinotecan) as initial therapy for older patients with metastatic colorectal cancer: NORDIC 9
BACKGROUND: Metastatic colorectal cancer (mCRC) is a disease of older age, but there is a relative lack of knowledge about effects of chemotherapy in older patients as they are under-represented in clinical trials. Little data can guide whether the strategy in older mCRC patients should be a sequent...
Autores principales: | Winther, Stine Braendegaard, Österlund, Pia, Berglund, Åke, Glimelius, Bengt, Qvortrup, Camilla, Sorbye, Halfdan, Pfeiffer, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559862/ https://www.ncbi.nlm.nih.gov/pubmed/28814275 http://dx.doi.org/10.1186/s12885-017-3526-8 |
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