Cargando…
Wnt signalling controls the response to mechanical loading during zebrafish joint development
Joint morphogenesis requires mechanical activity during development. Loss of mechanical strain causes abnormal joint development, which can impact long-term joint health. Although cell orientation and proliferation are known to shape the joint, dynamic imaging of developing joints in vivo has not be...
Autores principales: | Brunt, Lucy H., Begg, Katie, Kague, Erika, Cross, Stephen, Hammond, Chrissy L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560048/ https://www.ncbi.nlm.nih.gov/pubmed/28684625 http://dx.doi.org/10.1242/dev.153528 |
Ejemplares similares
-
Wnt16 Elicits a Protective Effect Against Fractures and Supports Bone Repair in Zebrafish
por: McGowan, Lucy M, et al.
Publicado: (2021) -
Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish
por: Kague, Erika, et al.
Publicado: (2019) -
The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis
por: Lawrence, Elizabeth A., et al.
Publicado: (2018) -
Finite element and deformation analyses predict pattern of bone failure in loaded zebrafish spines
por: Newham, Elis, et al.
Publicado: (2019) -
Zebrafish as an Emerging Model for Osteoporosis: A Primary Testing Platform for Screening New Osteo-Active Compounds
por: Bergen, Dylan J. M., et al.
Publicado: (2019)